A basic combo would be something like:
- Install Jackson Howard
- Power Shutdown R&D
Jackson shuffles 3 cards into R&D
- Accelerated Diagnostics into SEA Scorch Scorch
If you use Utopia before the Power Shutdown, you have a high chance to knock out one or both of Power Shutdown or AD, preventing the combo for the time being.
The ‘all-in’ option is to crack it before the AD, and if you hit the AD then you win the game (either by running Archives to collect many agendas, or waiting 3 turns for them to deck out). But if they had a 2nd copy of AD in hand or if you miss it, then they still get to combo off.
If you want to post an updated decklist, I’ll edit it in.
Sure, note that even with the Nerve Agent it’s still not favorable against NEH. If their asset economy starts rolling they don’t really care about Vamp, and running Femme as the only sentry breaker is just miserable against Architects.