The way I use it in this deck is a stack of:
- Ichi / Rototurret
- ETR ICE
- server contents
(eventually, I'll be adding another ICE on top of it, to eat Inside Jobs... but that usually isn't necessary until after the Inazuma is rezzed already)
That way, I get both flexibility in choosing which ICE to have Inazuma trigger onto, depending on what's best in the current situation (this particularly applies to situations where I can rez either the Ichi or the ETR, but not both), and also gives a bit more resilience to the Parasite issue you mention. It means I have to hold Inazuma in hand for a bit, but that's ok - I'm running enough ICE so that I never really have to use it sub-optimally.
Generally speaking, I'm playing NEXT to get an extra pseudo-turn of fortifying centrals (not necessarily to rush out an agenda on turn 2 or whatever). Won't be going for a remote play unless I can afford it (without compromising my position afterwards too much). People playing "rush decks" often literally forfeit the game by trying to rush-score before they're ready for the follow-up turns (and the runner's response). This might work for Astroscript because of how ridiculous that particular effect is, but with other agendas that doesn't work so much.
So, yeah - not going for scoring plays until I know the runner won't be able to punish me too hard for it. I might be willing to eat an Indexing or a Siphon to get EC scored, but not both.
She's a Rainbow that will also be a Destroyer and a Tracer. I mean... really? For 4 credits? With one sub? That doesn't seem worth the buff to the NEXT pieces I'll have rezzed. I will be of course testing her once she comes out, in her actual card pool - hard to properly evaluate now.
edit: Preliminary testing is done. Unfortunately, the ManUp version is tier 1.5 at best. Why oh why isn't ManUp a 5/2 like Fetal? That would have been so much better. Could have even been a 5/1 for all I care, but the 2 full turns of advancing just kill the poor thing. I'm most definitely not going to run Biotics just to get that stupid thing scored in 2 turns!