I think we are talking past your initial question @Cynchwyrm... "Does anyone see O2 Shortage as fitting in a Jinteki FA plan?" and you are right that the question "Do I want this or Neural EMP?" is kind of irrelevant because probably you wouldn't actually play O2 shortage without Neural EMP anyway.
I see O2 Shortage being good in a situation where I am set up the leverage both sides: if they take the random discard, I kill them... if they give me the free click, I am set up to use that. I don't think setting up situations where you are in a good position to fast advance AND you are in good position to get a flatline will come up often, especially if you are working with a 5 card hand.
So I have a lack of enthusiasm for O2 Shortage... I just am imagining all these games where the optimal situation to use it just doesn't come up, so I am forced to either play it when the runner has one correct option and hope the runner picks wrong, or just stare at it in my hand all game and eventually discard it (oh, and once I discard it, that's when I find myself with the runner with one card in hand, a Neural EMP, and a 3/2 agenda).
Thinking about it, O2 Shortage might be better in a net damage kill deck than a fast advance deck... O2 Shortage could give you the clicks to maybe get a Ronin into kill range or Archived Memories a Neural EMP a few times maybe? It'll certainly be more at home there than in a Jinteki Fast Advance deck, which can be a little spiky but not nearly as much as a deck playing stuff like Fetal AI.