The only real issue I can see is that she's 50 cards -- a balancing choice made, I assume, because at 45 she was too consistent to be balanced.
So, yeah, going to be doing a Valencia Combo deck, myself, and looking pretty forward to doing so.
EDIT: Also, the great thing with Itinerant Protestors is that it's set up from the get-go. If you can play it and Investigative Journalism on turn one, on turn three they'll be at a 3 card handsize if they haven't managed to score already, which certainly isn't impossible.
That's obviously an ideal situation, but once the handsize starts shrinking, Wanton Destruction and Legwork get much better, Dunno if the "reduce HQ size to 0" plan is enough to really help win things, but it's certainly not nothing, especially with Blackmail around to allow for instant access on scoring remotes.